Gene expression profiling of human adrenocortical tumors using cDNA microarrays identifies several candidate genes as markers of malignancy
نویسندگان
چکیده
INSERM EMI 01-05, Department of Cell Regulation and Dynamics, Commissariat à l’Energie Atomique (CEA), Grenoble, France Department of Integrative Biology, University Hospital of Grenoble, France COMETE : The French Network for Studies on human adrenal cortical and medullary tumors Transcriptome Analysis Platform, Genopole Rhône-Alpes, University Hospital of Grenoble, France INSERM ERIT-M 02-06, University of Méditerranée, Marseille, France Department of Endocrinology, Cochin Hospital, Paris, France Department of Hypertension, European Hospital Georges Pompidou, Paris, France Department of Endocrine Cancerology, Gustave-Roussy Institute, Villejuif, France Laboratory of Functional Endocrine Explorations, Trousseau Hospital, Paris, France Department of Endocrinology, University Hospital of Grenoble, France
منابع مشابه
Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy.
The aim of this study was to identify predictor sets of genes whose over- or underexpression in human sporadic adrenocortical tumors would help to identify malignant vs. benign tumors and to predict postsurgical metastatic recurrence. For this, we analyzed the expression of 230 candidate genes using cDNA microarrays in a series of 57 well-characterized human sporadic adrenocortical tumors (33 a...
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